منابع مشابه
Bacterial membrane lipids: diversity in structures and pathways.
For many decades, Escherichia coli was the main model organism for the study of bacterial membrane lipids. The results obtained served as a blueprint for membrane lipid biochemistry, but it is clear now that there is no such thing as a typical bacterial membrane lipid composition. Different bacterial species display different membrane compositions and even the membrane composition of cells belo...
متن کاملConformation and packing of membrane lipids: Crystal structures of lysophosphatidylcholines
H. Eibl Max-Planck-Institut ffir Biophysikalische Chemie Postfach 2841 D-37018 G6ttingen Germany Abstract The molecular conformation and packing of three lysophosphatidylcholines: 3-palmitoyl-D-glycero1phosphocholine (PPC), 3-hexadecylD-glycero1-phosphocholine (HPC) and 3-palmitoyl-DL-glycero1phospho-N,N-dimethylethanolamine (PPEM2) have been determinated by X-ray single crystal analyses. PPC c...
متن کاملInvolvement of membrane lipids in protein export in Escherichia coli.
Several models for the transport of proteins across membranes predict a role for lipids. If these models are correct, then alterations in lipid metabolism may affect protein export and vice versa. We are investigating this possibility by studying Escherichia coli K-12 mutants with defects in protein export or phospholipid metabolism. A temperature-sensitive secA mutant, which is defective in pr...
متن کاملInfluences of membrane mimetic environments on membrane protein structures.
The number of membrane protein structures in the Protein Data Bank is becoming significant and growing. Here, the transmembrane domain structures of the helical membrane proteins are evaluated to assess the influences of the membrane mimetic environments. Toward this goal, many of the biophysical properties of membranes are discussed and contrasted with those of the membrane mimetics commonly u...
متن کاملMembrane traffic: Cycling lipids
One of the more fascinating problems in biology is to understand the nerve signalling that enables us to think and feel. The transmission of nerve impulses across synapses is accomplished by the release of signalling molecules, known as neurotransmitters, at nerve terminals. Neurotransmitters are stored in synaptic vesicles and, after the nerve has received the appropriate stimulus, they are re...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2004
ISSN: 0005-2736
DOI: 10.1016/j.bbamem.2004.06.012